Treatment and etiological study on spinal deformities

 

Prof. Yong QIU

scoliosis2002@sina.com

 

From late 1990s on, our team have completely committed to establishing spinal correction technique for Chinese patients with spinal deformities. Posterior segmental multi-rod technique was set up for severe spinal deformity. Judging from the clinical and radiological features of the Chiari malformation patients with syringomyelia and scoliosis, we divided them into groups and made up a systemic treatment which harvested good outcomes and caused few complications. After researching on the pathophysiology of the severe scoliosis patients with respiratory failure, we established a multi-means individualized treatment to improve their respiratory function. A safe way for anterior spinal correction was provided after the anatomical and radiological studies. We also developed a minimally invasive spinal correction technique through mini-incision with thoracoscope for thoracic scoliosis. And independently, we set up a minimally invasive anterior correction technique through mini-incision with diaphragm intact for tho-racolumbar scoliosis and anterior supportive fusion on the concave side for thoracolumbar kyphoscol-iosis. And we reported that the prolongation of latency and the decrease of the amplitude can be used as a signal of the spinal cord ischemic injury when patients underwent anterior spinal correction. Besides, we performed a systemic research on the etiology and pathogenesis of scoliosis. Three risk genes of AIS and the difference in histomorphometry and cellular activity between the anterior and posterior column in AIS patients were found by our team. These findings are very important for the carrying on of early-stage screening, diagnosis and treatment. And our team also provided a mechanism of scoliosis second-ary to syringomyelia: The enervation of paraspinal muscles can cause scoliosis. By the way, our team have set up the largest clinical and histological database in China.