Principal Investigator:
Prof. Chenyu ZHANG Prof. Jiarui WU
cyzhang@nju.edu.cn
Research Content & Progress:
We clarify Chinese type 2 diabetes genetic background; figure out mechanism of environmental factors like stress in insulin resistance, cognate interaction of genetic factors and environmental factors, and reveal occurrence and development of type 2 diabetes.
We find out cellular molecules changing regularity in tissues modulating glucose homeostasis in type 2 diabetes and its complications.
Taking metabolism as the theme, we clarify the molecular mechanism of those changes.
We have achieved a lot of important research results with independent intellectual property, including the potential drug target for prevention and treatment of type 2 diabetes; screen and reveal intervention efficacy of certain nutrients in type 2 diabetes development, so as to lay foundation for a novel method of early intervention and to provide a theoretical basis of making new strategy for prevention and cure of type 2 diabetes.
We establish a “Transformational Research “model tailored to Chinese conditions, and combine basal research with clinical application. We advance the development of systems biology for complex disease in China. We cultivate a number of top international diabetes research personnel.
