Study of Micro-nanofluidic Integrated System for Bioanalysis
Time:2015-08-07 03:22 Source:未知 Author:chenxiaoqing  Click: 1837

Principal Investigator:

Prof. Hongyuan CHEN
Research Content & Progress:
This program organizes some middle-aged and young scholars in related basic fields such as chemistry, informatics, life science, and nano-technology. It aims at the state’s requirement and the international forefield of microfluidics, studies the multiscaled interface characteristics, the rules of media transporta-tion and the control in micro/nano fluidic channels, to reveal the interface behaviours; it designs bio-mimic micro/nano fluidic chips, establishes integrated fabrication and channel modification methods; it develops the array detection techniques compatible to micro total analysis, and explores the detection of single molecule behaviour and the mechanism of molecular identification in limited threshold on nano channel space; it develops injection techniques for the nano-liter and pico-liter samples, and fabricates micro/nano fluidic systems with the integration of injection, accumulation, reaction, separation and detection units; it explores biomacromolecules and cells’ accurate orientation, 3D images, interactions and space-time identifiably stimulated responses, losing, separation and detection of the cell contents, and studies the mechanisms of cell growth, metabolization, fade and the interaction mechanism between medical molecules and cells. It enhances our country’s original innovation ability in micro/nano fluidic system, and establishes the base of techniques innovation for developing bio-chemical analysis tech-niques and analytical instruments of our country in the future.