Prof.Bi’s main research interests are in the field of environmental analytical chemistry, bio-electrochemistry, particularly focusing on the interaction of toxic metal ions and nano-particulates with some important biological molecules including proteins and DNA. By applying various modern analytical methodologies including electrochemical, spectrometric, chromatographic, magnetic methods, as well as combining with computer simulations and quantum chemical calculations, the structure and mechanism of action of metallobiomolecules are studied comprehensively. Now, he is carrying out a new research work toward to establish the novel electrochemical methods to monitor and detect the free radicals generated in the biological and environmental chemistry processes in situ, in order to further deep understanding of the effect of metal ions and organic molecules on the electron transfer rate through DNA.