Name: | Prof. Zhongzhou YANG |
Title: | Professor |
Affiliation: | National Resource Center for Mutant Mice |
Email: | zhongzhouyang@nju.edu.cn |
Research Interests: | Using mouse models, we study the mechanisms in heart development and disease pathogenesis to explore therapeutic methods and develop effective drugs. Our research is focused on the role of PI3K- AKT signaling pathway in cardiac development and disease aiming to uncover novel efficacious means and drugs to improve the situation of heart defects and pathological remodeling through targeting this signal transduction cascade. In addition, we investigate epigenetic regulation in heart development and disease. |
Name: | Prof. Changhong LIU |
Title: | Professor |
Affiliation: | Department: State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences |
Email: | chliu@nju.edu.cn |
Research Interests: | ● Fungal life in deep biosphere and their roles in biogeochemical cycle
The sub-seafloor biosphere is the biggest discovery that scientific ocean drilling project has ever made. Intense studies have been made on bacteria and archaea while fungi, which played an important role in organic decomposition, have not been received much attention and only a few of studies have been carried out on the fungi in shallow sediments (<1.0km). By joining IODP Expedition 337, we have got a series coal-bearing sediment samples (Oligocene ~ Miocene) down to 2.5 km below the ocean floor. A major focus of our research is to understand if and how fungi live and what roles do they play in the subseafloor environments.
● Transcriptional regulation of NRPS in prokaryotic microbes and molecular basis of interaction between microbes and host plants
Bacillus amyloliquefaciens is a new biocontrol agent that can be used to control many leaf and root fungal diseases due to the production of antifungal lipopeptides, which is synthesized by nonribosomal peptide synthetase (NRPS). A major focus of our research is to disclose the transcriptional regulatory network of NRPS in B. amyloliquefaciens using modern techniques, including RNA polymerase site mutation technique, transcriptomic analysis and interdisciplinary approaches. Moreover, we also interest to understand the molecular basis on the interaction among biocontrol agents, pathogens and host plants.
|
Name: | Prof. Shuqing AN |
Title: | Professor |
Affiliation: | School of Life Sciences |
Email: | anshq@nju.edu.cn |
Research Interests: | Focus on restoration and reconstruction of structure and function of vegetations, and 4 fields are included as the followings. 1、Wetland ecology and ecological engineering of wetland restoration: Tissue culture and mass propagation of plant tool species, wetland vegetation restoration, carbon/nitrogen/phosphorus/sulfur biogeochemical cycles in wetlands, treated wetland and constructed wetland, planning, design, environmental evaluation and of wetland reserves and parks, rehabilitation of wetland ecosystems. 2、Forest ecology and biodiversity conservation: Vegetation structure, dynamic changes, hydrological function, functional group restoration; loss and conservation of genetic diversity of rare, endangered and important species, trade-off between seeds and seedlings of tree species. 3、Conservation and reconstruction of freshwater forested wetland: Distribution pattern, reginal characteristics, mechanism of degradation and missing, identification of key dominant species, conservation, restoration and rehabilitation of freshwater forested wetlands. 4、Biological invasions in wetlands and global changes: Mechanism and management of Spartina alterniflora invasions, decline mechanism and population restoration of Spartina anglica, impact of Spartina invasions on circulation of key life-needed elements, trace gas release and global changes of Spartina saltmarshes. |
Name: | Prof. Xiang GAO |
Title: | Professor |
Affiliation: | National Resource Center for Mutant Mice |
Email: | gaoxiang@nju.edu.cn |
Research Interests: | The molecular mechanisms for controlling physiological homeostasis, as well as the causes for deleterious diseases related to such mechanisms. Also interested in the chromatin architecture modulation that affects coordinated gene regulation in the whole genome level and sophisticated epigenetic control. |
Name: | Prof. Ren Xiang TAN |
Title: | Chair Professor,Assistant of President |
Affiliation: | State Key Laboratory of Pharmaceutical Biotechnology, College of Life Sciences |
Email: | rxtan@nju.edu.cn |
Research Interests: | Discovery, bioactivity, biosynthesis, structure-activity relationship of novel molecules from plants and microbes. |
Name: | Prof. Qiang XU |
Title: | Professor |
Affiliation: | State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences |
Email: | qiangxu@nju.edu.cn |
Research Interests: | Selective regulation of immune responses, especially T cell-mediated immune response; Pathogenesis of cancer metastasis and its therapeutic agents; Cellular and molecular events based on small molecule compounds. |
Name: | Prof. Dacheng TIAN |
Title: | Professor |
Affiliation: | State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences |
Email: | dtian@nju.edu.cn |
Research Interests: | Molecular and genome evolution, plant resistance evolution and synthesis, insertion/ deletion genetics, and epigenetics. |
Name: | Prof. Zichun HUA |
Title: | Professor |
Affiliation: | State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences |
Email: | huazc@nju.edu.cn |
Research Interests: | Coupling and integration of apoptosis and cell proliferation, molecular mechanism of tumor metastasis, tumor biology therapy, development of targeting anticoagulant and anti-tumor bio-pharmaceuticals. |